The 106 York University bus route operates between Downsview Station on the Yonge-University-Spadina Subway and the York University campus, generally in a north-south direction. Accessible service is provided on the route. Downsview Station is an accessible subway station. Bike racks are available on this route.

One single service is operated: the 106 (Downsview Stn-York University) branch operates at all times, seven days a week.

Northbound 106 TO YORK UNIVERSITY

These buses operate from Downsview Station via west on Sheppard Avenue West, north on Sentinel Road, then looping clockwise via west and north on The Pond Road, and east and south on Ian Macdonald Boulevard to York University Common Area (north side).

Southbound 106 TO DOWNSVIEW STN

These buses operate from York University Common Area via south on Ian Macdonald Boulevard, west on The Pond Road, south on Sentinel Road, and east on Sheppard Avenue West to Downsview Station.

All buses on the route serve local bus stops along the route.